Patient Record · MRN SMC-226052

SYN-024

[SYN] Sierra Kepler · 56y · Male · Chinese · BMI 27.8 · ECOG 1

SMCAS - Sunway Medical Centre AS · Cardiothoracic Surgery · Dr. Rajesh Kumar

IA3 (T1c, N0)Disease-free

EGFR L858RTP53

Clinical storyline

[SYN] Sierra Kepler, a 56-year-old Chinese male (current, 24 pack-years, ECOG 1), presented in 2024-02 with unintentional weight loss (~5kg over 3 months). Workup confirmed Adenocarcinoma (Stage I, EGFR L858R). The MDT recommended curative-intent surgery. Current status: Disease-free.

HPE Results

Adenocarcinoma: Acinar

Clinical Stage

IA3 (T1c, N0)

Pathological Stage

IA3 (T1c, N0, Mx)

Adenocarcinoma Subtype

Acinar

CEA (ng/mL)

4.5

Tumor (CT/PET)

3.1 cm

PET SUV

3.63

NGS Results

1. EGFR Exon 21 Mutation (L858R)
2. TP53 R273H