Patient Record · MRN SMC-275576

SYN-036

[SYN] Bravo Xenon · 56y · Female · Chinese · BMI 25 · ECOG 1

SMCAS - Sunway Medical Centre AS · Medical Oncology · Dr. Lim Hui Yi

IIIC (T4, N3)Disease-free

EGFR L858RTP53

Clinical storyline

[SYN] Bravo Xenon, a 56-year-old Chinese female (current, 40 pack-years, ECOG 1), presented in 2025-11 with unintentional weight loss (~5kg over 3 months). Workup confirmed Adenocarcinoma (Stage III, EGFR L858R). The MDT recommended first-line osimertinib. Current status: Disease-free.

HPE Results

Adenocarcinoma: Acinar

Clinical Stage

IIIC (T4, N3)

Pathological Stage

IIIC (T4, N3, M0)

Adenocarcinoma Subtype

Acinar

CEA (ng/mL)

18.5

Tumor (CT/PET)

4.7 cm

PET SUV

11.48

NGS Results

1. EGFR Exon 21 Mutation (L858R)
2. TP53 R273H