Patient Record · MRN SMC-189842

Patient #046

Sharifah · 70y · Female · Malay · BMI 23 · ECOG 1

SMCAS - Sunway Medical Centre AS · Cardiothoracic Surgery · Dr. Faisal Hashim

IIB (T2a, N1)Disease-free

TP53

Clinical storyline

Sharifah, a 70-year-old Malay female (current, 42 pack-years, ECOG 1), presented in 2024-11 with right-sided chest discomfort. Workup confirmed Neuroendocrine / Carcinoid (Stage II, TP53). The MDT recommended curative-intent surgery. Current status: Disease-free.

HPE Results

Undifferentiated large cell malignancy in the lung, differential diagnoses include poorly differentiated adenocarcinoma, poorly differentiated SCC, high-grade neuroendocrine carcinoma, and large cell lymphoma. Further IHC analysis required for tumor characterization

Clinical Stage

IIB (T2a, N1)

Pathological Stage

IB (T2a, N0, Mx)

Adenocarcinoma Subtype

Large cell neuroendocrine carcinoma

CEA (ng/mL)

2.8

Tumor (CT/PET)

4 cm

PET SUV

12.05

NGS Results

TP53 mutation